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Solution & Service
Peptide CDMO Service

Built on integrated platforms for peptides, proteins, and oligonucleotides, Viva PPO offers end-to-end peptide CRDMO services from discovery to commercial GMP manufacturing.


Powered by AI-driven design and 'Lab-in-the-Loop' druggability profiling, we accelerate peptide development with robust libraries and synthesis capabilities. Our innovative hybrid (SPPS/LPPS) and continuous process technologies enable seamless scale-up from mg to thousand kg, while our GLP-1 readiness and expertise in oral peptide delivery support the advancement of next-generation peptide therapeutics.

Peptide Peptide
Peptide
  • ncAAs
  • Macrocycles
  • PDC
  • RDC(precursor)
  • 3-50aa
Protein Protein
Protein
  • mAbs
  • Bispecific antibodies
  • AOC
Oligonucleotide Oligonucleotide
Oligonucleotide
  • POC
  • ASO
  • siRNA
  • Aptamer
Project Experience
Building Block<br>LPPS/SPPS
Building Block
LPPS/SPPS

Non-Canonical Amino Acid

  • α,β,γ-substituted
  • N-alkylated
  • Pegylated

 

Peptide Fragment

  • Fmoc-AA1-AA2-OH
  • Fmoc-AA1-AA2-AA3-OH
  • Fmoc-AA1-AA2-AA3-AA4-OH
  • GLP-1 Fragments
Representative Generic Drugs by<br>Hybrid or SPPS Approaches
Representative Generic Drugs by
Hybrid or SPPS Approaches
  • Liraglutide
  • Atosiban
  • Semaglutide
  • Carbetocin
  • Tirzepatide
  • Linaclotide
  • Mazdutide
  • Octreotide
  • Leuprorelin
  • Lanreotide
  • Triptorelin
  • Pasireotide
  • Goserelin
  • Eptifibatide
  • Degarelix
  • Terlipressin
  • Cetrorelix
  • Teriparatide
  • Abaloparatide
NCE<br>PLatforms
NCE
PLatforms
  • POC
  • PDC
  • RDC
  • GLP-1
End-to-End Development Capabilities
Discovery
01
  • Target Investigation
  • HTS (DEL, Virtual Screening, etc.)
  • Biochemical and Cell-Based Assay for Validation
  • Early SAR Studies
  • Lead Candidate Selection
  • Route Selection & Sample Preparation
Learn More
Early Phase
02
  • Lead Optimization
  • Process Development
  • Method Development
  • Formulation Development
  • Toxicology & Safety Studies
  • CMC & Regulatory Preparation
Late Phase
03
  • Tech Transfer & Optimization
  • SJR & QRA Study
  • Method & Process Validation
  • GMP Manufacturing
  • Stability Study
  • Regulatory Submission
  • Commercial Readiness
From Discovery to Commercial Manufacturing
Peptide Facilities
Process R&D
Crude Peptide: 40kg/a
Bulk Peptide: 20kg/a
Process R&D Process R&D
Shanghai GMP
Crude Peptide: 20kg/a
Bulk Peptide: 10kg/a
Shanghai GMP Shanghai GMP
Zhejiang GMP
Crude Peptide: 1,000-2,000kg/a
Bulk Peptide: 350-700kg/a
(Phase 1 Capacity)
Zhejiang GMP Zhejiang GMP
Process Process R&D GMP Production
Synthesis Liquid Phase Peptide
Synthesis (LPPS)

Reactor size is

up to 30L

The batch size is

up to 30L

200-5000L
Solid Phase Peptide
Synthesizer (SPPS)
Manual:100mL-5L
Automatic Peptide Synthesizer
 
10L Line 
20L Line

20/50L Line

200L Line
500L Line

1000L Line (Planning) 
2000L Line (Planning) 

Purification

Prep-HPLC

(High Pressure)

DAC 50 

DAC 100
DAC 150

10L Line 
20L Line
DAC 200/300
DAC 450
DAC 600  
DAC 900 (Planning) 
Isolation Lyophilizer 0.5m2

3m2

5m2, 10m2, 20m2
Process2 Process R&D GMP Production
Synthesis Liquid Phase Peptide
Synthesis (LPPS)

Reactor size is

up to 30L

The batch size is

up to 30L

200-5000L
Solid Phase Peptide
Synthesizer (SPPS)
Manual:100mL-5L
Automatic Peptide Synthesizer
 
10L Line 
20L Line

20/50L Line

200L Line
500L Line

1000L Line (Planning) 
2000L Line (Planning) 

Purification

Prep-HPLC

(High Pressure)

DAC 50 

DAC 100
DAC 150

10L Line 
20L Line
DAC 200/300
DAC 450
DAC 600  
DAC 900 (Planning) 
Isolation Lyophilizer 0.5m2

3m2

5m2, 10m2, 20m2
Process3 Process R&D GMP Production
Synthesis Liquid Phase Peptide
Synthesis (LPPS)

Reactor size is

up to 30L

The batch size is

up to 30L

200-5000L
Solid Phase Peptide
Synthesizer (SPPS)
Manual:100mL-5L
Automatic Peptide Synthesizer
 
10L Line 
20L Line

20/50L Line

200L Line
500L Line

1000L Line (Planning) 
2000L Line (Planning) 

Purification

Prep-HPLC

(High Pressure)

DAC 50 

DAC 100
DAC 150

10L Line 
20L Line
DAC 200/300
DAC 450
DAC 600  
DAC 900 (Planning) 
Isolation Lyophilizer 0.5m2

3m2

5m2, 10m2, 20m2
Case Study
  • Case Study: GLP-1 Analog
    GLP-1 Diabetic Area

     

    GLP-1 analogues can be prepared in kg scale with a purity of ≥ 98% or higher by SPPS or hybrid.

  • Case Study: Radionuclide Drug Conjugates (RDC)
    Precursors of Lutathera
    Case Study: Radionuclide Drug Conjugates (RDC)
    • Process R&D: Assembling strategy; trouble shooting on racemization in amide formation
    • Analytical method development and validation
    • Develop reverse-phase purification method with final lyophilization
    • Comparative study on quality consistency